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In addition, some heavy metal responsive transcription factors can also be induced by other abiotic stresses such as cold, dehydration, Salicylic Acid (SA) and H 2 O 2 , suggesting cross-talk exists between heavy metal response and other abiotic stress defense signalling (Fusco et al., 2005, Singh et al., 2002, Suzuki et al., 2001, Weber et al., 2006)

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This review provides an updated, mechanistic evaluation of these developments, with particular emphasis on how defined structural attributes influence antimicrobial activity, organelle-specific targeting, and integrated imaging-therapy platforms