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a severe flare is diagnosed when the SLEDAI score has increased by 12 or more points

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For example, many lipolytic proteins such as PLIN1 (13, 130), PNPLA2 (131, 132) and G0S2 (133) are stabilized by condition that promote LD biogenesis, such as oleic acid supplementation, where association with the phospholipid monolayer is thought to mask motifs that signal degradation