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No BPC-157 is described as a fragment of naturally occurring gastric body protection compound, but its origin story is unusually murky The alleged parent protein has never been fully characterized And BPC-157 itself doesn’t clearly match any known human gastrointestinal peptide or any other human protein When asked why the full protein sequence has never been published, the scientist who discovered BPC-157 said, “ If you have your own child, you want it to be yours forever .” He has also refused to disclose the screening method used to originally identify the compound So this isn’t just a case of missing data The details appear to be deliberately withheld This is basically the scientific equivalent of, “ Trust me, bro .” Several mechanisms have been proposed Particularly effects involving VEGF (vascular endothelial growth factor), angiogenesis, nitric oxide, and neurotransmitter systems But none of those have been established in humans And we do not know the receptor or target through which the drug principally operates Peter has heard people defend BPC-157 as a peptide without a receptor, leaning on the fact that some drugs genuinely do not work through receptors That part is true, but that is the sleight of hand You see lacking a receptor is different from lacking a mechanism A molecule can act without a classic receptor and still have a well-defined mechanism of action Most molecules that end up showing clinical benefit do have a mechanism of action
