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Those who received MK-677 experienced a 40 percent increase in serum insulin-like growth factor I (IGF-I) and a significant increase in serum IGF-binding protein-3, especially during the second and eighth weeks

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Thus, it can be hypothesized that the ability of DSIP to maintain efficiency of oxidative phosphorylation, even in the setting of hypoxia, could make the peptide a subject of interest for conditions such as stroke and heart attack in future research