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Spinal manipulation (chiropractic adjustment) addresses this neurological root cause by: Restoring normal joint motion at the dysfunctional spinal segment Normalizing mechanoreceptor input from joint capsule proprioceptors to the spinal cord Reducing gamma motor neuron hyperactivity in the associated spinal segment Decreasing muscle spindle sensitivity in the associated myotome Reducing sympathetic tone in the spinal cord segments adjacent to the dysfunctional joint, which contributes to the overall sensitization state A 2018 systematic review by Pasquier et al