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Decreases in the mucin layers have been shown to compromise the intestinal barrier function leading to increases in intestinal permeability and microbe penetration [129]
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2020) and PARP10, which inhibit activation of NF-κB and downstream target genes in response to IL-1β and TNF-α in a manner that depends on its catalytic activity and poly-ubiquitin binding activities (Verheugd et al
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