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The criteria are defined by the Diagnostic and Statistical Manual for Mental Disorders (DSM-5) for a diagnosis of autism spectrum disorder: A.Persistent deficits in social communication and social interaction across multiple contexts, as manifested by the following, currently or by history (examples are illustrative, not exhaustive, see text): Deficits in social-emotional reciprocity, ranging, for example, from abnormal social approach and failure of normal back-and-forth conversation

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Recently, an ancient insertion fingerprint in the tRNA was discovered that gives credence to the idea of the addition of the anticodon section (along with the D arm) to the older fragment comprising the CCA stem (and the T arm) (120)