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We found a significant reduction in cathelicidin antimicrobial peptide (CAMP) (log2 fold = − 3.743, P = 0.038) and placenta enriched 1 (PLAC1) (log2 fold = − 7.071, P = 0.032) GP levels 1 week after 4-week intermittent fasting compared with the levels before 4-week intermittent fasting