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Notably, the activation of UPR is intimately related to three transmembrane ER-resident stress sensors: inositol-requiring enzyme 1 (IRE1), PKR-like ER kinase (PERK) and activating transcription factor (ATF6), which acts as regulators of cell fate under ER stress by integrating information about the intensity and duration of the injury

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Regenerative Peptides Regenerative peptides come from wound-healing research, not from cosmetics