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These ROS, in turn, amplify AGE–receptor for AGE (RAGE) signaling, establishing a vicious cycle wherein oxidative damage and inflammation reinforce one another, exacerbating renal injury (35)
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To dissect the upstream regulatory mechanism of miR-29b-3p under Gln deprivation conditions, we integrated transcriptome data (GSE148016) from both Gln+ and Gln- groups, and performed cross-analysis with the predicted upstream transcription factors of miR-29b-3p, ultimately identifying five candidate transcription factors
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