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Since January 2026, there have been six cases of acute liver toxicity associated with unapproved peptide products labelled Retatrutide in Australia. These toxic effects may be linked to a contaminant in the

Based on these findings, the authors suggest that modulating the Mff-linked Pum2 level/activity using genetic or pharmacological approaches may restore ageing-related mitochondrial damage, which represents a novel way for anti-aging strategy [236]

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doi: 10.1073/pnas.1107386108

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