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Similar principles would apply for the dithiol oxidoreductases, which also contributes to the thermodynamics and kinetics of their thiol–disulfide interchange reactions
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The selumetinib prescribing information includes warnings and precautions for cardiomyopathy, ocular toxicity, gastrointestinal toxicity, skin toxicity, increased creatine phosphokinase, increased levels of vitamin E, and increased bleeding risk (capsules), and embryo-fetal toxicity
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