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The efflux mechanism in resistant breast cancer is usually achieved by overexpression of ABC transporters such as P-glycoprotein (P-gp) which can lower drug accumulation inside the cell by removing the anticancer drugs out of cells is the most popular resistance mechanism (Seelig and Gatik-Landwojtowicz, 2005)
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Saved COA records are a critical compliance artifact for any lab that runs documented studies
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