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Semaglutide is a relatively stable peptide, but aggressive agitation creates shearing forces that can degrade any protein-based molecule
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Kruger et al., also reported that IGF-1R activation rather than IGF-1R overexpression is sufficient to induce downstream activation of the MAPK/PI3K signalling pathways and overcome tamoxifen treatment in breast cancer (Kruger et al., 2020)
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