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GH secretagogues including ipamorelin are also contraindicated for subjects with cancerous conditions, due to their potential to elevate GH levels, accelerate cell growth, and impact disease progression
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A previous limitation of the metalloporphyrin class of compounds has been their poor oral bioavailability, but several compounds in the AEOL 112-series have been shown to have good oral bioavailability and longer plasma half-lives which should make them better candidates for treating chronic diseases [22]
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