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Therefore, the present study investigated whether BSO induced ferroptosis in cancer cells, and whether the cellular glutathione level may be a marker for GCLC inhibitor-sensitivity

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36 The induction of MPTP will eventually cause the release of multiple important mitochondrial proteins into the cytoplasm, such as apoptosis-inducing factor (AIF), endonuclease G (Endo G), and cytochrome c (Cyt C)

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