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Redirecting Biosynthetic Pathways with Precursors The simplest and most classic method to diversify the structures of natural products from a producing organism is through the alteration of precursors and/or biosynthetic intermediates
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It has been found that the thioredoxin reductase system and glutathione peroxidase system play an important role in cellular oxidative stress defense ( 2- ), H 2 O 2 , and hydroxyl radicals (OH − )
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