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PLS also contained puerarin (22) and daidzin (23), which significantly inhibited mushroom tyrosinase activity (with IC 50 values of 478.5 μM and 17.50 μM, respectively)
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In different cell types, activation of necroptosis can be triggered by death receptors of the TNF family, including TNF receptor superfamily member 1A (TNFRSF1A/TNFR1), FAS, and TNF-related apoptosis-inducing ligand (TRAIL) receptors (TNF receptor superfamily member 10a [TNFRSF10A/TRAILR1] and TNF receptor superfamily member 10b [TNFRSF10B/TRAILR2]), that typically induce apoptosis
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