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Version 1.0: Communication based on AHLs In our first version of the design, we aimed to establish bidirectional communication between Lactobacillus plantarum and Escherichia coli using AHL-based signaling: Nissle 1917 was engineered to express the LuxI protein, enabling synthesis of a small, diffusible signaling molecule— 30C6-HSL , an acyl-homoserine lactone (AHL)
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