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The use of histamine H 2 -receptor antagonist, pharmaceuticals that decrease gastric acid secretion parietal cells, including cimetidine (Tagamet), famotidine (Pepcid), nizatidine (Axid) and ranitidine (Zantac) may exacerbate impairments in vitamin B12 absorption from food in older adults, but rarely induce deficiency alone
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