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Lyme disease is an infectious illness caused primarily by Borrelia burgdorferi and transmitted by infected black-legged ticks

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Molecular techniques included chromatin immunoprecipitation (ChIP) using antibodies against H3K79me2 (Abcam) to study histone modifications, and RNA sequencing (RNA-seq) to analyze gene expression profiles in CD8+ T cells exposed to varying methionine and SAM conditions