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Neuroendocrine System Both epithalon and melatonin can mitigate several age-related aspects of neuroendocrine dysfunction and restore the normal circadian rhythm of gonadotropin-releasing hormone [7]

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“We think that the [neurons’ influence] on intervertebral disc degeneration is not only limited to the occurrence of pain, but also intervertebral disc degeneration itself,” said Ximing Xu, professor in the Department of Orthopedic Surgery in Changzheng Hospital, and co-lead author of the study