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The percent of cartilage injuries treated ranged from 13.8 to 22.1% during this time period, yet only 1% of these repair procedures involved advanced techniques such as chondrocyte transplantation

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Because the brain has high energy demands, limited energy reserves, and an abundance of phospholipids that serve as substrates for oxidative damage, it is especially vulnerable to disruptions in iron metabolism and the resulting oxidative stress (Altahrawi et al., 2025)